/ Thesaurus / S Synonyms of santa fe trail Find synonyms for: Noun1. Santa Fe Trailusage: a trail that extends from Missouri to New Mexico; an important route for settlers moving west in the 19th centuryWordNet 3.0 Copyright © 2006 by Princeton University. All rights reserved. Related Content Daily Word Quiz: nefarious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language